Besides retaining the lovable, gentle traits of the Great Dane, the mixes would also display attributes of its other parent like the Great Danoodle may come with the Poodle-like intelligence or the Doberdane would display the Doberman’s aggression.
- Labradane: Great Dane x Labrador
- Daniff: Great Dane x Mastiff
- Boxane: Great Dane x Boxer
- Weiler Dane: Great Dane x Rottweiler
- Great Danoodle: Great Dane x Poodle
- Doberdane: Great Dane x Doberman
- Saint Dane: Great Dane x St. Bernard
- American Dane: Great Dane x American Bulldog
- American Foxy Dane: Great Dane x American Foxhound
- Great Dasenji: Great Dane x Basenji
- Great Pyredane: Great Dane x Great Pyrenees
- Great Danesky: Great Dane x Siberian Husky
- Great Weimar: Great Dane x Weimaraner
- Plush Danois: Great Dane x Anatolian Shepherd Dog
- Great Dane Bull: Great Dane x Pit bull
- Great Shepherd: Great Dane x German Shepherd
- Great Bullweiler: Great Dane x Bullmastiff x Rottweiler
- Irish Dane: Great Dane x Irish Wolfhound
- Bull Daniff: Great Dane x Bull Mastiff
- Great Golden Dane: Great Dane x Golden Retriever
- Italian Daniff: Great Dane x Cane Corso
